Johnson & Johnson and Delta variant. The American company assures that its single-dose is effective because it develops “neutralizing antibody activity at an even higher level than that recently observed for the Beta variant in South Africa, where it has been shown to be highly effective against severe forms of the disease. “. Duration of immunity “The humoral and cellular immune responses generated by Janssen’s single-dose anti-Covid vaccine lasted for at least 8 months” according to “the latest observation reported to date”. “The data showed that T cell responses – including CD8 + cells that recognize and destroy infected cells – are persistent over the 8 months tested.” “The current data so far reaches 8 months of observation and shows that Johnson & Johnson’s single dose vaccine against Covid-19 generates a strong neutralizing antibody response that does not decrease over time; indeed, an increase is observed – says Mathai Mammen. Global Head, Janssen Research & Development, J&J – In addition, we note a persistent and particularly robust and long-lasting cellular immune response. “” With each new dataset – he concludes – we strengthen the evidence base that demonstrates that our single-dose vaccine against Covid-19 plays a key role in ending the pandemic, which continues to evolve and pose new challenges to global health “. What it contains” COVID-19 Vaccine Janssen is a vaccine used to prevent COVID-19, a disease caused by the virus SARS-CoV-2. COVID-19. The vaccine causes the immune system (the body’s natural defenses) to produce antibodies and specialized white blood cells that act against the virus, off I protect against COVID-19. None of the components of this vaccine can cause COVID-19, “reads the package leaflet. “The active principle – it continues – is a type 26 adenovirus, which encodes the spike glycoprotein of SARS-CoV-2 * (Ad26.COV2-S), not less than 8.92 log10 infecting units (U. Inf .) * in each 0.5 mL dose. * Produced in the PER.C6® TetR cell line and by recombinant DNA technology. This product contains genetically modified organisms (GMOs). The other ingredients (excipients) are: – pack of 10 vials: 2-hydroxypropyl-β-cyclodextrin (HBCD), citric acid monohydrate, ethanol, hydrochloric acid, polysorbate 80, sodium chloride, sodium hydroxide, trisodium citrate dihydrate, water for injections (see section 2 “COVID19 Vaccine Janssen contains sodium “And” COVID-19 Vaccine Janssen contains ethanol “). – Pack of 20 vials: 2-hydroxypropyl-β-cyclodextrin (HBCD), citric acid monohydrate, ethanol, hydrochloric acid, polysorbate 80, sodium chloride, sodium hydroxide, water for injections (see section 2 “COVID-19 Vaccine Janssen contains sodium ”and“ COVID-19 Vaccine Janssen contains ethanol ”)”. Side Effects Like all vaccines, COVID-19 Vaccine Janssen can cause side effects, although not everybody gets them. Most of the side effects occurred within 1-2 days of vaccination – Blood disorders: Following vaccination with COVID-19 Vaccine Janssen, blood clots have been observed very rarely in association with low levels of platelets (cells that help blood clotting) in the blood. This condition includes severe cases of blood clots even in unusual sites such as the brain, liver, intestines and spleen, in some cases with the presence of bleeding. These cases occurred in the first three weeks after vaccination and mainly in women under 60 years of age. This condition has also resulted in death.The leaflet instructs you to seek immediate medical attention if, after a few days of vaccination, severe or persistent headaches, seizures (convulsions), changes in mental status or blurred vision occur, if they appear. unusual bruising on the skin somewhere other than the vaccination site, very small round spots other than the vaccination site or if you experience shortness of breath, chest pain, leg pain, leg swelling or persistent abdominal pain. Also inform the healthcare professional (doctor, pharmacist or nurse) that you have recently received COVID-19 Vaccine Janssen – Seek immediate medical attention if, within 3 weeks of vaccination, you experience any of the following symptoms: severe or persistent headaches, blurred vision, changes in mental status or seizures (convulsions); wheezing, chest pain, leg swelling, leg pain, or persistent abdominal pain; unusual bruising on the skin or very small round spots located somewhere other than the vaccination site. Get urgent medical attention if you have symptoms of a severe allergic reaction. These reactions may include a combination of some of the following symptoms: – feeling faint or light-headed – changes in heart beat – wheezing – wheezing – swelling of the lips, face or throat – hives or rash – nausea or vomiting – stomach pain The following side effects may also occur with this vaccine: Very common (may affect more than 1 in 10 people): headache, nausea, body aches, pain where the injection is given, sensation extreme tiredness Common (may affect up to 1 in 10 people): redness where the injection is given, swelling where the injection is given, chills, joint pain, fever, cough. may affect up to 1 in 100 people): rash, muscle weakness, pain in arms or legs, feeling of weakness, generally feeling unwell, sneezing, sore throat, pain in the hiena, tremor, excessive sweating Rare (may affect up to 1 in 1000 people): allergic reaction, hives Very rare (may affect up to 1 in 10,000 people): blood clots often in unusual sites (eg. brain, intestine, liver, spleen) associated with low blood platelet levels Not known (frequency cannot be estimated from the available data) severe allergic reaction.
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