AstraZeneca, Pfizer, Moderna: second dose and news Cts

Stop the AstraZeneca vaccine for those under 60. The decision comes after the news relating to the rare cases of thrombosis that have occurred in recent weeks. And for those under 60 who have already taken the first dose with the Anglo-Swedish company’s drug, the second will be from Pfizer or Moderna. General Francesco Paolo Figliuolo communicated the news after the recommendations from the CTS. AstraZeneca and the recommendations of the CTS “The CTS recommended for the first doses of vaccinations to reserve the doses of AstraZeneca for those who are 60 years of age or older. While for the under 60s even in the absence of worrying warning signs , the recommendation is for heterologous vaccination “, Cts coordinator Franco Locatelli said at the press conference to update the vaccination campaign.” In this epidemiological context, the CTS has changed in close dialogue with Aifa and the other health institutions in the country. considered it appropriate to re-evaluate the indications for the use of the AstraZeneca vaccine because, having changed the scenario, the relationship between benefits and potential risks associated with rare thrombosis changes according to age but also to the changed scenario “, added Locatelli. Son:” Impact on the campaign vaccines “The decision to administer the AstraZeneca vaccine only to the over 60s, after the rare cases of thrombosis that occurred in ul time weeks, “it will have some impact on the vaccination plan” but “I am sure that between July and August we will be able to mitigate if not eliminate this impact”, said Figliuolo.
Hope: “Peremptory CTS recommendations” The recommendations of the CTS on the AstraZeneca vaccine, which will be administered only to over 60s, with booster with other mRna vaccines for young people who have already received the first dose, “will be translated in a stringent manner”. Thus the Minister of Health, Roberto Speranza, in a press conference in the multipurpose room of the Presidency of the Council The regions are reorganizing From Lombardy to Lazio passing through Piedmont, the regions have already partially reorganized according to the new indications on the AstraZeneca vaccine. From today, “according to the provisions of the Technical Scientific Committee, the second doses to people over 60 vaccinated with Astrazeneca will be made with the same vaccine. The boosters of people under 60 vaccinated in the first dose with Astrazeneca will instead be made with another vaccine”, he said. announced in a note by the Welfare DG of the Lombardy Region. “New provisions of the Ministry of Health on the use of the anti-Covid vaccine Vaxzevria (AstraZeneca): from tomorrow (today, ed) it will be administered exclusively to citizens over 60 (starting from 60 years already completed). Those under 60 will only receive an mRna vaccine (Pfizer -BionThec or Moderna), even those who have received the first administration of Astrazeneca “, clarified the councilor for health of the Lazio Region, Alessio D’Amato .
“We are ready to immediately implement Commissioner Figliuolo’s provisions on Astrazeneca. There are about 37 thousand second doses of Astrazeneca scheduled for the next weeks for citizens under 60: they will be given Pfizer or Moderna according to national guidelines. We are talking about a quantity that is absolutely compatible with our stocks, this indication of the Scientific Technical Committee will therefore not impact our vaccination campaign, the appointments will not be postponed “, declared the Councilor for Health of the Puglia Region Pier Luigi Lopalco. from the national health authorities the official note relating to the new methods of use of the AstraZeneca vaccine, the Piedmont Region has decided as a precaution to suspend the administration of the first doses and recalls of Astrazeneca to the under 60 population, announced a note in which it is specified that “as soon as the procedure for carrying out the boosters of AstraZeneca through the Pfizer and Moderna alternative vaccines will be clarified with an official note from the national health authority, the Region will immediately implement the reprogramming of the second doses”. “In compliance with the indications received today by the Technical Scientific Committee ei n waiting for the specific ministerial circular, the administration of the Vaxzevria vaccine by AstraZeneca is suspended in Sicily, also in second dose for all subjects under 60 years “, also announced the Department of Health of the Sicily Region.
Ema: “No AstraZeneca to those who have increased capillary permeability” The Prac Pharmacovigilance Committee of the European Medicines Agency Ema has established that “people who have previously had capillary permeability syndrome should not be vaccinated with Vaxzevria *”, the AstraZeneca anti-Covid vaccine. This was reported by the EU regulatory body. Capillary leak syndrome – he explains in a note – is a very rare and serious condition that causes fluid loss from small blood vessels (capillaries), resulting in swelling, mainly in the arms and legs, low blood pressure, increased density of the blood and low blood levels of albumin (an important blood protein). The EMA Committee decided that capillary leak syndrome should be “added to the ‘Product Information’ as a new side effect of AstraZeneca’s Covid vaccine , Vaxzevria *, along with a warning to raise awareness among healthcare professionals and patients about this risk. “

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