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AstraZeneca vaccine: Guillain-Barré syndrome listed as “very rare” side effect – The HuffPost

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RODRIGO GARRIDO / Reuters

Guillain-Barré syndrome is now listed as a “very rare” side effect of the AstraZeneca vaccine by the European Medicines Agency (illustrative photo taken in Valparaiso, Chile, in August).

CORONAVIRUS – The European Medicines Agency (EMA) listed, this Wednesday, September 8, Guillain-Barré syndrome, a rare neurological impairment, as a “very rare” side effect of the vaccine against covid-19from AstraZeneca.

According to the EMA, 833 cases of the neurological syndrome have been reported worldwide as of July 31, while more than 592 million doses of Vaxzevria serum, from the AstraZeneca laboratory, have been administered worldwide as of July 25. July.

“The EMA Pharmacovigilance Risk Assessment Committee (PRAC) concluded that a causal relationship between Vaxzevria and Guillain-Barré syndrome is considered at least a reasonable possibility,” said the European regulator in a press release.

“Guillain-Barré syndrome should therefore be added to the product information as a side effect of Vaxzevria,” said the agency, headquartered in Amsterdam. The frequency category assigned is “very rare”, that is, occurring in less than 1 in 10,000 people.

This was already the case for the Janssen vaccine from Johnson & Johnson

Guillain-Barré syndrome is an attack on the peripheral nerves characterized by weakness or even progressive paralysis, most often starting in the legs and sometimes going up to reach the muscles of breathing then the nerves of the head and neck. .

The EMA has recommended an update to a warning that has been included in the product information since July to raise awareness of the risks among healthcare professionals and those receiving the vaccine. The warning also reminds patients to seek immediate medical attention if they develop weakness and paralysis of the extremities which may progress to the chest and face.

The European regulator had listed Guillain-Barré syndrome in July as a “very rare” side effect of the anti-covid-19 vaccine from Johnson & Johnson, using the same adenovirus technology as the Vaxzevria serum.

The US Medicines Agency also warned in July of an “increased risk” of developing neurological syndrome with Johnson & Johnson’s serum. Both regulators had clarified that the vaccine’s benefits outweighed the potential risks.

See also on the HuffPost: The ups and downs of AstraZeneca, the “unloved” vaccine

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