NewsWorldA highly neutralizing antibody capable of attacking all variants...

A highly neutralizing antibody capable of attacking all variants of SARS-CoV-2 – Yahoo News


There are currently four variants of concern (VOC) and four variants of interest (VOI) of SARS-CoV-2. These variants have in common increased transmission and partial resistance to vaccines and certain antibody-based treatments. While the pandemic is not slowing down, others will emerge in the future.

To deal with this problem, the High Authority of Health recommends the injection of a third vaccine dose for people 65 years and over, and those who have a significant risk of declaring a severe form of Covid-19. The third dose should be spaced at least six months after the second. But this is not the only strategy being investigated.

Two publications, published a few days apart in Immunity, each present a highly neutralizing antibody effective against SARS-CoV-2 variants.

The SARS2-38 binding site on the RBD. The celadon blue lines indicate the light chain of the antibody and the dark blue lines indicate the heavy chain. The green dotted lines show the site of interaction with the ACE2 receptor. © Laura A. VanBlargan et al. Immunity

Target a conserved region of protein S

The first monoclonal antibody, called SARS2-38, was isolated by a team from the Washington School of Medicine. It is the only one, among the 43 isolated from the serum of mice immunized with the receptor binding domain (RBD) of the coronavirus, to keep its neutralizing activity for all variants. Indeed, SARS2-38 binds with great affinity to part of RBD, the region of the S protein in physical contact with the ACE2 receptor, which varies very little between the variants. Thus, although many variants have one or more mutations in RBD, the efficacy of SARS2-38 is not affected.

Scientists have shown that SARS2-38 can neutralize all variants tested in vitro, namely the major variants Alpha, Beta, Delta and Gamma and other minor variants such as the Iota and Kappa variants. From…

Read more on Futura “class =” link rapid-noclick-resp “>> Read more on Futura

Read also on Futura


  1. Download Giriu Dvasios – Dub Vibes, Vol. 4 Album Mp3 Zip
    Download Various Artists – Pals Vol. 5 Album Mp3 Zip
    Download Amulet – Un Desert De Colors Album Mp3 Zip
    Download Amalekim – Hvhi Album Mp3 Zip
    Download Austeen – Premier Virage Album Mp3 Zip
    Download Sax Efrain Acosta – Sax Dance, Vol. 2 – EP Album Mp3 Zip
    Download Peha & Solaw – Minds Off – EP Album Mp3 Zip
    Download Alexander Kielland Krag & Emelie Hollow – this stays between us Album Mp3 Zip
    Download Dillinger – Under the Blue Light Album Mp3 Zip
    Download Sweden Laundry – Lyrical 2 – Pieces of You – EP Album Mp3 Zip
    Download Michael Foster & Ben Bennett – Contractions Album Mp3 Zip
    Download Omega – Mambo Todo El Año (Radio Edit) Album Mp3 Zip
    Download Verschillende artiesten – Rough Cuts Vol.1 Album Mp3 Zip
    Download Various Artists – Dansbandsnytt volym 2 Album Mp3 Zip
    Download Roque Baños – 30 Monedas (Música Original del Episodio 8 de la Serie) (Vol. 8) Album Mp3 Zip
    Download Various Artists – Arabian Gold Album Mp3 Zip
    Download Various Artists – The Earthquake Album Mp3 Zip
    Download Asphyxiate – Altar of Decomposed Album Mp3 Zip
    Download Various Artists – Hommage à Petit Pays, vol. 1 Album Mp3 Zip
    Download Blödbüse – Blödbüse Album Mp3 Zip
    Download Nightfall in Eden – The Great Darkness Album Mp3 Zip
    Download DJ Glen – Every Hi-End is a New Beginning Album Mp3 Zip
    Download Pye Corner Audio – Black Mill Tapes (10th Anniversary Box) Album Mp3 Zip
    Download Armand Hammer – Paraffin (Instrumentals) Album Mp3 Zip
    Download Dimitri Vegas & Like Mike – Home Alone (On the Night Before Christmas) (Dj Mix) Album Mp3 Zip

Comments are closed.

Latest news

Mariupol, over 100 bodies found under rubble

Over one hundred bodies were found under the rubble of a bombed building in Mariupol, in the Livoberezhny district....

Mercato / Ligue 1 – Real, Chelsea, Barça, Juve …: For Neymar, options in question – Eurosport FR

ChelseaWhy is it possible?Chelsea have changed eras. But his ambitions remained intact. To afford Neymar would allow...

Drought, Curcio: “Water rationing during the day is not excluded”

"In some areas of the country we cannot rule out water rationing and therefore the closure of distribution during...

Italy in the grip of Charon, expected temperatures over 40 ° C

The African anticyclone Charon continues to hold Italy hostage: even in the week that has just begun, the thermometers...

You might also likeRELATED
Recommended to you