The European Medicines Agency (EMA) decided to ban the use of zinc oxide in therapeutic concentrations for the treatment of pigs from July 1, 2022. The logic behind this ban is based on the premise that the risks of this metal burdensome to the environment outweigh the benefits of zinc oxide in mitigating post-weaning diarrhea and edema disease. According to Ceva Animal Health, weaning piglets without the use of zinc is a challenge that all European pig producers are now facing. To address this challenge, the ‘Zero Zinc Summit’ was held on June 22-23 in Copenhagen, giving researchers, veterinarians and producers the opportunity to review alternative strategies on how to wean piglets without the use of zinc and with consumption minimum of antibiotics in the weaning period, maintaining animal welfare, minimum environmental impact and high productivity. Ceva attended the summit and contributed significantly to answering these questions. Two posters were presented on the treatment of iron deficiency and coccidiosis in the lactation period to ensure stable and well-developed piglets at weaning, a highly stressful period for the animals. Three other posters by Ceva together with its collaborating partner the ‘Freie Universität Berlin’ addressed the high prevalence of Shiga toxin (up to 50%) in pig farms and the risk factors that an outbreak is more likely when strategies are used. without zinc oxide and with low consumption of antibiotics. Thus, they affirm that the need to replace these protocols with updated strategies was highlighted, such as improvements in management and vaccination against edema disease offered by Ceva with Ecoporc shiga, a toxoid vaccine against shiga toxin.