NewsWorldA study detects the monkeypox virus in anal samples...

A study detects the monkeypox virus in anal samples of asymptomatic people

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A study from Bichat-Claude Bernard Hospital in Paris, France, has detected monkeypox virus in anal samples from asymptomatic men who have sex with men (MSM). These results suggest that vaccination limited to those with known exposure to monkeypox virus may not be enough to prevent infection, according to the study, published in the Annals of Internal Medicine. The researchers retrospectively tested for monkeypox virus with PCR. in all anorectal swabs that were collected as part of a screening program for sexually transmitted infections. According to French guidelines, this type of screening is performed every 3 months among MSM with multiple sexual partners taking HIV pre-exposure prophylaxis (PrEP). ) or living with HIV and receiving antiretroviral treatment. Of the 200 asymptomatic people tested who were negative for ‘N. gonorrhoeae’ and ‘C. trachomatis’, 13 (6.5%) samples were PCR positive for monkeypox virus. Two of the 13 people subsequently developed symptoms of monkeypox. Whether asymptomatic infection plays a role in the transmission of monkeypox virus is unknown. But the current global epidemic of monkeypox and the person-to-person mode of transmission may provide evidence that asymptomatic or preclinical spread may occur. The researchers suggest that “an expanded strategy of ring vaccination and other public health interventions in the highest-risk communities to help control the outbreak.

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