For Moderna’s Covid vaccine an efficacy of 93%, lasting for 6 months after the second dose. This is the figure that emerges from the final analysis of the results of the Phase 3 Cove study, communicated by the American company as part of the presentation of company updates and financial results for the second quarter of 2021. Moderna has received the emergency authorization for the ” use of your vaccine in adults by regulatory bodies in more than 50 countries and the emergency use list by the World Health Organization (WHO), as well as the green light for use in adolescents aged 12 and over, in EU and Japan. On June 1, the company began the process to obtain full and definitive authorization for the vaccine in the US (Bla, Biologics License Application) and expects to complete the submission process by August. Meanwhile, Moderna is also working with other regulatory bodies to authorize or approve the product in other jurisdictions. Meanwhile, the company has completed enrollment and a phase 1 study is underway for a next-generation Covid vaccine (mRna-1283) potentially stable in the refrigerator, a quality that could facilitate distribution and storage. In this next-generation vaccine candidate (which encodes portions of the Sars-CoV-2 Spike protein crucial for neutralization, particularly Rbd and Ntd), the encoded antigen is shorter than that of the current mRna- 1273. Its characteristics could facilitate the ‘logistics’ of this product and also its administration by healthcare professionals, explains the company.
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