The debate among experts is ignited on the anti-covid vaccine for children and young people under 12 years of age. In the US, the FDA has urged manufacturers to expand the audience for clinical studies on the efficacy of mRna vaccines in the 5-11 year range. According to some scientists, vaccinating children is a mandatory step in achieving herd immunity. Others, however, preach prudence. “Considering the current state of the art, it does not seem to me that pressure elements are identified that would make pediatric vaccination against Covid a topic of significant interest, so much so as to make it a priority in prevention protocols. Unless we are dealing with children with a known history of diseases that require special attention especially on the immunological side or of children who live with ‘fragile’ adults unable to get vaccinated “, says to Adnkronos Salute the clinical immunologist and allergist Mauro Minelli, coordinator for Southern Italy of the Foundation for Personalized Medicine. “Rather, the primary objective in the agendas of the bodies in charge remains the complete coverage of the entire adult population, considering that today in the population over the age of 60, there are still more than 2 million people never vaccinated and therefore at risk to contract the disease in a severe form, and just under 2 million with incomplete vaccination “, remarks Minelli. Virologist Francesco Menichetti also expresses “some perplexity about anti-Covid vaccines for very young children”. “I still am not completely convinced that it is a qualifying target”, underlines the head of infectious diseases at the Pisa hospital. “Now we will see the data, the registration studies will be important, however – clarifies Menichetti – even more important than the registration studies will be to clarify what the vaccination policy will be. If we want to achieve herd immunity and at what level”. Because, explains the virologist, “we could already achieve important results if we put the 5 million over 50s and children aged 12 and over in safety to reopen schools”. “In short – he reiterates – I would be a little cautious on the little ones”. The reason is always based on the risk / benefit ratio “which is usually lowered for children”. “That is – explains the doctor – even if the risk remains the same, it is more relevant with the decrease in age. If the epidemiology of Covid confirms this trend, it is right that the vaccination policy takes it into account”. “I am not convinced that children are at risk or that they are the drivers of the infection. The drivers of the infection – says the head physician – are young unvaccinated adolescents and young adults, as we are seeing in recent weeks and months. It is true that an 11-year-old girl died yesterday, but she was a girl who had a very serious problem, therefore a fragile subject. I am referring to healthy children, the fragile follow another path “. On the possibility of vaccinating children between 6 and 12 years of age against Covid, when there is authorization, “scientific evidence remains our guide. When these have shown us that the vaccine is effective and safe, we can start vaccinations and, obviously, we will be active and present in the vaccination campaign, as was already the case in the age group between 12-16 years “, explains Paolo Biasci, president of the Italian Federation of pediatricians (Fimp). “Even when we waited for the validation of the trials on 12-16 years – continues Biasci – we expressed ourselves only after having known the experimental results, the possible side effects, the efficacy rates and all the rest. Without knowing these data today on immunization of children to express themselves is impossible. We can hope that the results of the experimentation are positive. And that therefore there is an approval by the regulatory agencies, the EMA and then Aifa for use under 12 years and when it will be, I don’t think before the end of the year from the news we have, we will also consider vaccination in this age group “. For adolescents over 12 “we started vaccinating but we regret not being able to start the effective vaccination immediately, after the green light of the AIFA, because the Regions have created delays. We could have been more advanced in carrying out the vaccinations”. Immunologist Paolo Rossi from the Bambino Gesù pediatric hospital expresses himself in favor of vaccinating under-12s: “If we want to fight this pandemic – he explains – and we want to return to a normal life we must achieve community immunity and if we leave it out children and we do not vaccinate them we cannot achieve this community immunity. So I personally am in favor of vaccination and as an immunologist I would also have been in favor of compulsory vaccination because vaccines have saved the world. And in a situation like the one we are experiencing, I would not I would have had no doubt. ” “This virus is unfortunately extremely contagious and therefore – Rossi points out – it infects as we know, even this age group quite easily. In most cases these children from one year up to 12-13 years do not have major problems, they have an infection without major consequences but they are super loudspeakers so since they then have to go to school, being loudspeakers becomes a problem both for school and for older people “. “Now – recommends the pediatrician – we must immediately vaccinate children between the ages of 12 and 16, because at that age they also have symptoms and some are also important. While the concept of community is valid for the younger group, that is the risk / risk ratio. the benefit of the individual is still good, the vaccine does not have an important side effect but it is difficult to say that it prevents a serious disease on the child. school and for others “. “How to convince mothers? I would tell them that if they do not want their children to have the Invalsi level of first grade when they are in sixth grade and if they want to prevent the little ones from infecting the older ones, they must be vaccinated. against everything because – he concludes – against Covid-19 no? “. Massimo Galli is also on the same line of thought:” Once the studies have guaranteed the safety for the administration of the anti-Covid vaccine even to under 12s it will be inevitable to pass immunization of the little ones. Because if all over the world we let the virus circulate among children, without any form of containment, we will no longer stop it. Vaccinating everyone is the only way to stop it “, says the director of Infectious Diseases at the Sacco hospital in Milan. As for the parents’ concerns, Galli recalls that, at all ages, “scientific observations suggest that the best thing, given its characteristics, is not to encounter this virus”. And on the other hand, “the available vaccines have been used on tens of millions of people all over the world. And they have shown a very high safety margin, probably higher than that of vaccines previously used for other diseases”. Furthermore, “the aim of reducing the circulation of the virus as much as possible is fundamental, both as regards collective interests and for individual interests. believes the risks of vaccines – argues Galli – know that, with the rapid spread of the Delta variant which also affects children, it is not possible to expect that their child will not become infected because he is protected by the vaccination of others. to vaccination and the real risks associated with the disease, I choose vaccination “.
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