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Pfizer, 21 days or 42 between doses? Locatelli: “Vaccine remains effective”


An interval of 6 weeks – not 21 days – between the first and second dose of the covid Pfizer vaccine does not reduce efficacy. Professor Franco Locatelli, president of the Higher Council of Health, thus expresses himself on the strategy that provides for a distance of 42 days between the two doses of the drug. Pfizer, even in the last few hours, has instead reiterated the indication to administer the second dose 21 days after the first. “As a doctor, I answer very clearly: the interval between the first and second administration of the” anti-Covid mRna vaccine “extended to the sixth week, therefore to 42 days, does not in any way affect the efficacy of immunization and allows us to be able to administer many more doses of the vaccine, “Locatelli said at Agorà. Read also “I understand that those who work in the industry have very protective attitudes towards the studies conducted and these studies mainly concerned a 21-day interval” between the two doses, “but real life studies that have accumulated have indicated exactly that. that I said before and statements like the ones we heard yesterday “from Pfizer” are only likely to create bewilderment and I think they would hopefully be avoidable, “he adds.
SECOND DOSE, WHAT PFIZER SAYS “The vaccine was designed for a second administration at 21 days. Data on a longer range of administration at the moment we have none except in real life observations, as was done in the UK. And ‘an evaluation of the CTS that has its basis, we will observe what happens. Like Pfizer, however, I say to stick to what has emerged from the scientific studies, therefore the administration at 21 days, because this guarantees the results that allowed the authorization ” Valeria Marino, medical director of Pfizer, Italy, told Sky Tg24 yesterday about the lengthening of the window for the administration of the second dose. “We must also study the need for the third dose – added Marino -. We have the data that prove it. immune coverage at six months, we must observe the following six months. A third dose may be possible but perhaps also not necessary, unless there are any variations, in q u in case a ‘buster’ dose might be useful. On the annual vaccine – he concluded – we must be very cautious, it may be necessary within the year or maybe within two “. VACCINE TO CHILDREN” It is clear that by vaccinating “against Covid” also the adolescent age and in the future the pediatric age will be reduced further viral circulation, another reason to encourage the spread of a vaccination campaign even under the age of 18 or 16 as in the case of Pfizer “, observes Locatelli on the subject of vaccination of the under 18s and on the green light in the US by the FDA to Pfizer vaccine in the 12-15 year range. “It is indubitable that the pediatric range is largely spared from serious or even fatal cases of Covid – he says – but there have been some rare cases and that single case counts for that family. This is already enough and advances to underline the importance of vaccine validation even in adolescence “.

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