Pfizer vaccine, news from the company today on the efficacy against variants, but also news from Italy on the timing of the second dose – which in Lazio will postpone to 5 weeks -, the Aifa report on the reports of adverse reactions in our country and the chronicle, with what seems to be the first case in the world of overdose with 6 doses of the product mistakenly administered to a trainee from Massa. Here is the news of the day in detail. Read also Pfizer and variants: “No need to adapt the vaccine” For now there is no need to adapt the Pfizer BioNTech anti covid vaccine in the face of the onset of variants. “At the moment, there is no evidence that the current BioNTech vaccine needs to be adapted to the variants that have emerged,” reads a BioNTech release, with first quarter earnings figures. In the first three months of the year, it says, the company had an income of over two billion euros, while profits were 1.13 billion. In the first quarter of 2020, BioNTech had an income of 27.7 million, the jump is naturally due to the Covid vaccine. “BioNTech has continued to globally distribute our covid 19 vaccines to more than 90 countries and territories. Through continuous innovations, we expand access to new populations and places, addressing emerging variants,” said company head Ugur Sahin.Pfizer, in Lazio postpone the second dose “Starting from Monday 17 May, the calls of the Pfizer vaccine will be extended to 5 weeks, or 35 days”. This was announced by the Covid crisis unit of the Lazio Region. “All interested parties will be notified in advance via SMS – he informs in a note – and the extension, taking into account the recommendations of the Technical Scientific Committee (CTS) and the Commissioner Structure, will allow an increase in the audience of the first doses of Pfizer vaccine starting already from the current month, or by causing an increase in population coverage. No changes, however, at the moment, for all the other vaccines “.” By way of example – clarifies the Crisis Unit – who had to call Pfizer on May 17 will always be in the same place and at the same time on May 31, and so on “. Pfizer and vaccines: adverse reactions reported in Italy Between December 27, 2020 and April 26, 2021 for the four vaccines in use in the current vaccination campaign are received 56,110 reports out of a total of 18,148,394 doses administered (with a reporting rate of 309 per 100,000 doses), of which 91% refer to non-serious events, which resolve comp lethally, such as injection site pain, fever, asthenia / fatigue, muscle aches. This is what emerges from the fourth Pharmacovigilance Report on Covid-19 vaccines published by the Italian Medicines Agency, relating to reports of suspected adverse reactions registered in the National Pharmacovigilance Network. they occur mostly on the same day of vaccination or the day after (85% of cases). Most of the reports are related to Pfizer / BioNTech’s Comirnaty vaccine (75%), so far the most used in the vaccination campaign (70.9% of administered doses), and only to a lesser extent to AstraZeneca’s Vaxzevria vaccine (22%) and the Moderna vaccine (3%), while there are no reports relating to Covid-19 Vaccine Janssen, J&J (0.1% of the doses administered) in the period considered. ‘Aifa – is conducted with the support of a’ Working group for the evaluation of thrombotic risks from anti-Covid-19 vaccines’, made up of some of the leading national experts in thrombosis and haemostasis.Pfizer, overdose by mistake in Massa: 6 doses together with trainee It looked like a vaccination like many others, of those intended for healthcare personnel. A few minutes after the injection, however, a shocking revelation was made to the young clinical psychology trainee from Massa: “We were wrong. We injected her with the entire vial of Pfizer vaccine, equal to six doses”. It happened yesterday morning at the New Apuan hospital (Noa) in Massa as reported today by ‘La Nazione’. Just enough time to metabolize the news, a frantic series of talks with health and doctors and then hospitalization for observation, where the young woman should remain until today. The condition of the 23-year-old last night was fair and the girl is kept under control not so much for the current state of her health, as for the fact that – to date – there seems to have never been an inoculation of six doses of the vaccine. A similar case has occurred in recent months in Germany, but in that case there were five doses, while the Pfizer trial relating to overdose would stop at four. In the absence of a series of cases, the unfortunate trainee is kept under close observation, a report on what happened has already been sent to Aifa and yesterday morning even police personnel went to the hospital to get information on what happened.