“Invoking a lockdown in 2022 is foolish”. Word of the virologist Guido Silvestri, professor at Emory University in Atlanta, who explains why in the current phase of the Covid-19 epidemic the closures are “unsustainable”, while the right way is to push even more on vaccinations. “In a population that is not infinite – writes the founder of the social page ‘Pills of optimism’ on Twitter – a virus that spreads at great speed tends to rapidly exhaust the subjects susceptible to infect. It is the reason for the lockdowns, as well as unsustainable, they do not have exit strategies, as the pool of susceptibles remains intact. In reality, the lockdowns made sense in these three conditions: initial emergency; hope of reaching Covid-zero; absence of alternatives (vaccines). This was the situation in March 2020 “, profoundly different from the current one. “Vaccines, on the other hand, are not only a sustainable solution, but effective in the long term – underlines the scientist – as they directly reduce the pool of susceptible to infection and in any case, in the worst case, they significantly reduce the pool of susceptible to developing disease. How nice it would be – Silvestri hopes – if, instead of making stupid and useless polemics, we could all internalize these simple concepts and work together to: increase vaccination coverage in the population; dissuade politicians from any closure temptation “.