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Covid vaccine, fourth dose will be done? And when? What the experts say


Dec 4, 2021

The vaccination campaign is progressing with the third dose, necessary, the experts underline, also in light of the Omicron variant. And we are looking at a fourth dose of the Covid vaccine in 2022. “For now, from what emerges, the Omicron variant would seem more contagious, but with milder cases. We do not yet know definitively whether it can dodge the vaccine, but if should it do so it would not be in complete form, which is why it is necessary to take the third dose “, Fabrizio Pregliasco, the medical director of the Irccs Galeazzi Orthopedic Institute in Milan, told iNews24. Read also Yesterday the President of the Higher Health Council Franco Locatelli spoke of a fourth dose as a concrete probability. “It is clear that in 2022 we will do a fourth dose” of vaccine for Covid-19, “we only need to understand when, I do not think it will be done in the first months of the new year for those who have and he is now taking the third dose – Matteo Bassetti, director of the Infectious Diseases Clinic at the Policlinico San Martino hospital in Genoa, told Adnkronos Health – We will have to wait for the results of the studies, see how long the immunity of the complete cycle lasts with 3 doses and then evaluate when the fourth will be needed “. “Probably a fourth dose will be done – continues Bassetti – with an improved vaccine adapted to the variants. Omicron, more contagious than the Delta, does not seem to me to be a relevant problem from a clinical point of view, it is not giving devastating clinical pictures, so I relatively worried “. In any case, for the infectious disease specialist the concrete probability of a fourth dose “shouldn’t be a problem: if doing the fourth dose means having the current Covid-19 numbers and continuing to live with the virus by weakening it, I don’t think the Italian citizens will have problems if they are told to get vaccinated for the fourth time in 2022. The attitude of ‘ah, but you made us do 3 doses, now even a fourth’ is wrong, because it is a closed attitude towards progress of medicine and science. Everyone is free to think what they want, but this will be the medical recommendation “, he remarks. The immunologist Mauro Minelli, head of the Foundation for personalized medicine for Southern Italy, at Adnkronos Salute underlines that “it is in the most critical moments that the value of those who decide and the effectiveness of their decisions are assessed and measured, which cannot change once a month. Otherwise, more than decisions they become kabbalistic options of the type ‘let’s try and see how it goes. Then if it doesn’t go, let’s change’. would the opportunity and timing to proceed with a new possible recall be verified in the field (having at the moment only ‘prophecies’ and not univocal, consolidated and numerically credible certainties? “. For Minelli there are many questions still unanswered. “Why not develop a laboratory method – he asks – that can give reliable information on the dynamics of immunization, useful, if not to hopefully customize vaccination procedures, at least to obtain well-founded feedback on which to schedule any next doses? How should those recovered from Covid-19 regulate themselves? By chance, as if natural immunity, albeit robust and reassuring, were an optional addendum, even knowing the great unlikelyness that a recovered from Covid-19 could get sick again from the same disease? “. “And is it possible that in a community of states gathered in a supranational economic and political aggregation – the immunologist asks – each member state decides on its own, generating different readings of a single phenomenon and consequent so heterogeneous provisions? a central body has been set up which decides univocally for the whole European continent, and those who move across the border in Europe must refer to the old refrain ‘Country you go, customs you find’ for a socio-health phenomenon which, instead, it is always the same at every latitude “. For the councilor for health and social and health integration of the Lazio Region, Alessio D’Amato, “it is premature to talk about the fourth dose. Our technicians at the Spallanzani Institute tell us that the goal is to get an annual recall with vaccines updated to variants, such as the flu vaccine “.

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