“It is clear that in 2022 we will do a fourth dose” of vaccine for Covid-19, “we just need to understand when, I don’t think it will be done in the first months of the new year for those who have done and are now doing the third dose. We will have to wait for the results of the studies, see how long the immunity of the complete cycle lasts with 3 doses and then evaluate when the fourth will be needed “. Matteo Bassetti, director of the Infectious Diseases Clinic at the San Martino Polyclinic in Genoa, has no doubts, thus commenting to Adnkronos Health the statements of the President of the Higher Health Council Franco Locatelli, who speaks of a fourth dose of Covid vaccine- 19 as a concrete probability. “Probably a fourth dose will be done – continues Bassetti – with an improved vaccine adapted to the variants. Omicron, more contagious than the Delta, does not seem to me to be a relevant problem from a clinical point of view, it is not giving devastating clinical pictures, so I relatively worried “. In any case, for the infectious disease specialist the concrete probability of a fourth dose “shouldn’t be a problem: if doing the fourth dose means having the current Covid-19 numbers and continuing to live with the virus by weakening it, I don’t think the Italian citizens will have problems if they are told to get vaccinated for the fourth time in 2022. The attitude of ‘ah, but you made us do 3 doses, now even a fourth’ is wrong, because it is a closed attitude towards progress of medicine and science. Everyone is free to think what they want, but this will be the medical recommendation “, he remarks.