Vaccine Johnson & Johnson, how long it lasts. MRna call: circular

Booster with mRna vaccine – Pfizer or Moderna – for those who have received the Johnson & Johnson covid vaccine. The booster dose – which Lazio is ready to administer – must be injected at least 6 months after inoculation of the Janssen vaccine, which guarantees an immune response for up to 8 months and protects against serious disease for at least 6 months. The circular from the Ministry of Health arrives and establishes that “all subjects vaccinated for at least six months (180 days) with a single dose of Janssen vaccine will be able to receive a booster dose with m-Rna vaccine in the dosages authorized for the booster (30 mcg in 0.3 mL for Pfizer / BioNTech’s Comirnaty; 50 mcg in 0.25 mL for Moderna’s Spikevax) “. Read also The indication of the Technical Scientific Commission of AIFA, the drug agency, has been received: the body has considered that “for subjects vaccinated with Covid-19 Janssen it is appropriate to administer a heterologous booster dose with mRna vaccine (in the dosages authorized for the booster dose) starting from 6 months from the first dose “.” It can be considered a consolidated strategy for most vaccines – reads an Aifa note – the opportunity to provide a booster dose appears supported by a solid rationale. The most recent evidence confirms the efficacy of a booster dose (especially with mRna vaccine) in enhancing the immune response to the Covid-19 Janssen vaccine. “In recent days, the protection guaranteed by the vaccine has been discussed. single-dose, thanks to some declarations relating to a ‘coverage’ of just 2 months. “The available data indicate a substantial stability of the immune response, both humoral and cellular, up to 8 months after the administration of a dose of Janssen vaccine. Also the protection against serious illness, hospitalization or death is substantially stable up to at least 6 months after vaccination “, the CTS of Aifa found,” on the basis of the in-depth investigation “. “At the same time, however, with the passing of the months a slow decline in vaccination efficacy is observed – it is emphasized – against mild / moderate forms of the disease”. J&J VACCINE IN LAZIO Lazio is ready “for the administration of the booster 180 days “of the Johnson & Johnson vaccine” immediately with general practitioners and within 48 hours by booking on the regional portal and in pharmacies “. The operation “affects an audience of about 200 thousand people”, underlines the regional councilor for health, Alessio D’Amato, in the daily Covid bulletin. SPUTNIK AND SINOVAC The booster dose is also destined to be approved for other vaccines. ” The CTS of Aifa has decided to suggest the opportunity of a vaccination booster, that is a booster dose, six months after the completion of the complete vaccination cycle with J & j for vaccinated subjects. It was decided to open the possibility of a booster dose for vaccinated people with other vaccines: Sputnik or Sinovac will have this opportunity and this possibility “, Nicola Magrini, director general of Aifa, told Tg1. Meanwhile, news on the Russian vaccine Sputnik. The ‘light’ version “demonstrates a high safety profile and induces a strong antibody and cellular immune response” according to a study by the Gamaleya Center, published in ‘Lancet’ and promoted by the Russian Direct Investment Fund (Rdif). some of the adverse reactions observed during the study “were mild or moderate. No serious adverse events were detected “. Sputnik Light” is a ‘one-shot’ vaccine or with a single administration and has been authorized in more than 15 countries “, underlines the Gamaleya Center on its website, recalling as previous analyzes” have shown that Sputnik Light, given alone, is 70% effective against Delta variant infection during the first three months after vaccination. “The effectiveness of Sputnik Light,” as a booster against Delta variant for others. vaccines, should be close to that of the Sputnik V vaccine against the Delta variant: over 83% for infection and over 94% for hospitalization “.