A blood sample personalizes post-stroke recovery, Maugeri study

After a stroke, a blood sample can help predict the patient’s response to therapies, so as to personalize the rehabilitation process. This is the perspective that opens thanks to a study by the Laboratory of Nanomedicine of the Maugeri Clinical Scientific Institutes (ICS) of Pavia, presented at the Bio-Sensing Tech-nology conference in Sitges in Spain, an international event in which the most recent research is discussed. in the field of biosensors, health-tech and new point-of-care diagnostic technologies. The work involved 55 patients enrolled within 24 hours of the onset of ischemic symptoms, and blood samples were collected in the acute phase, after 7 days, after 30 days and 3 months from the first clinical manifestations. For the presentation of the results obtained on the quantification of biomarkers of brain damage, the researcher Marta Truffi was awarded with an Award for Outstanding Rapid Communication. “An unexpected joy – he comments – an award that I consider assigned to our whole group and that pushes us to continue with ever greater determination. The pandemic has slowed down our work – he underlines – We worked hard due to the contingent accesses in the departments and for the difficulty in the Covid-19 era of follow-ups, but we went ahead with conviction “. The data illustrated at the conference – reads a note – derive from the use of an ultra-sensitive digital technology called Single Molecule Array (Simoa), available at the ICS Maugeri Nanomedicine Laboratory, for the detection of biomarkers in blood samples of patients recruited within a clinical protocol coordinated by Irccs Maugeri, in collaboration with the Policlinico San Matteo and the Irccs Mondino of Pavia. The study also involved the Research Laboratory on Neurodegenerative Diseases and the Maugeri Neurorehabilitation Units. “This research, which looks at stroke damage and recovery – concludes Truffi – could have very important implications for personalizing patients’ care and allowing them appropriate care and better recovery. We are ready to work on a third biomarker to strengthen the level. forecast, and extend it to 6 months after the ischemic event “.

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